Article
Identification of novel SNPs in glioblastoma using targeted resequencing.
PloS one - 1 Jan 2011
Keller Andreas, Harz Christian, Matzas Mark, Meder Benjamin, Katus Hugo A, Ludwig Nicole, Fischer Ulrike, Meese Eckart
Abstract excerpt
High-throughput sequencing opens avenues to find genetic variations that may be indicative of an increased risk for certain diseases. Linking these genomic data to other "omics" approaches bears the potential to deepen our understanding of pathogenic processes at the molecular level. To detect novel single nucleotide polymorphisms (SNPs) for glioblastoma multiforme (GBM), we used a combination of specific target...
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