Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

PloS one - 1 Jan 2022

Williams Gareth, Llewelyn Alexander, Thatcher Robert, Hardisty Keeda-Marie, Loddo Marco

Abstract excerpt

The standard treatment for glioblastoma involves a combination of surgery, radiation and chemotherapy but have limited impact on survival. The exponential increase in targeted agents directed at pivotal oncogenic pathways now provide new therapeutic opportunities for this tumour type. However, lack of comprehensive precision oncology testing at diagnosis means such therapeutic opportunities are potentially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Biomarkers, Tumor
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Phosphatidylinositol 3-Kinases

Share to Precision Medicine

Source

Open in PubMed Open full text

Identifiers

PMID: 35324914
DOI: 10.1371/journal.pone.0245817
PMCID: PMC8947072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.PMID 35324914Read ↗

Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastomaSemantic proximity Read ↗

Multigene profiling to identify alternative treatment options for glioblastoma: a pilot study.Semantic proximity Read ↗

Functional Precision Oncology: The Next Frontier to Improve Glioblastoma Outcome?Semantic proximity Read ↗

Use of personalized molecular biomarkers in the clinical care of adults with glioblastomasSemantic proximity Read ↗

Prospective, high-throughput molecular profiling of human gliomas.Semantic proximity Read ↗

Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making.Semantic proximity Read ↗

Clinical Impact of a Next-Generation Sequencing Approach for Glioblastoma PatientsSemantic proximity Read ↗

Toward precision medicine in glioblastoma: the promise and the challenges.Semantic proximity Read ↗

Utilisation of semiconductor sequencing for detection of actionable fusions in solid tumoursSemantic proximity Read ↗

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.Semantic proximity Read ↗

A wide spectrum of EGFR mutations in glioblastoma is detected by a single clinical oncology targeted next-generation sequencing panel.Semantic proximity Read ↗

Actionable molecular alterations in newly diagnosed and recurrent IDH1/2 wild-type glioblastoma patients and therapeutic implications: a large mono-institutional experience using extensive next-generation sequencing analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.