Article
SSBP2 variants are associated with survival in glioblastoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2012
Xiao Yuanyuan, Decker Paul A, Rice Terri, McCoy Lucie S, Smirnov Ivan, Patoka Joseph S, Hansen Helen M, Wiemels Joe L, Tihan Tarik, Prados Michael D, Chang Susan M, Berger Mitchel S, Kosel Matthew L, Fridley Brooke L, Lachance Daniel H, O'Neill Brian Patrick, Buckner Jan C, Thompson Reid C, Nabors Louis Burt, Olson Jeffrey J, Brem Steve, Madden Melissa H, Browning James E, Wiencke John K, Egan Kathleen M, Jenkins Robert B, Wrensch Margaret R
Abstract excerpt
PURPOSE: Glioblastoma is a devastating, incurable disease with few known prognostic factors. Here, we present the first genome-wide survival and validation study for glioblastoma. EXPERIMENTAL DESIGN: Cox regressions for survival with 314,635 inherited autosomal single-nucleotide polymorphisms (SNP) among 315 San Francisco Adult Glioma Study patients for discovery and three independent validation data sets [87...
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