Article
Association of polymorphisms in FLT3, EGFR, ALOX5, and NEIL3 with glioblastoma in the Han Chinese population.
Medical oncology (Northwood, London, England) - 1 Dec 2013
Jin Tian-Bo, Li Xiao-Lan, Yang Hua, Jiri Mutu, Shi Xu-Gang, Yuan Dong-Ya, Kang Long-Li, Li Shan-Qu
Abstract excerpt
Glioblastoma (GBM) is the highest-grade glioma in astrocytoma. Patients often have poor prognosis due to therapeutic resistance and tumor recurrence. Identification of the genetic factors of GBM could be important contribution to early prevention of this disease. We genotyped 17 tag single-nucleotide polymorphisms (tSNPs) from nine genes in this study, including 72 cases and 302 controls. SNP genotyping was...
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