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Article

Disruption of cerebellar granule cell development in the Pax6 mutant, Sey mouse.

Brain research. Developmental brain research - 7 Dec 2005

Swanson Douglas James, Tong Yiai, Goldowitz Dan

Abstract excerpt

The transcriptional regulator Pax6 is expressed in cerebellar granule cells and a mutation in that gene (Sey) has been shown to affect cerebellar development. We have defined novel phenotypes in the Sey/Sey cerebellum, indicating that the mutation of Pax6 alters granule cell behavior in vitro and also the interaction between granule cells and Purkinje cells in vivo. In culture, Sey/Sey granule cell precursors...

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Identifiers

PMID: 16289327
DOI: 10.1016/j.devbrainres.2005.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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