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Article

Linkage and association analysis of hyperthyrotropinaemia in an Alpine population reveal two novel loci on chromosomes 3q28-29 and 6q26-27.

Journal of medical genetics - 1 Aug 2011

Volpato Claudia B, De Grandi Alessandro, Gögele Martin, Taliun Daniel, Fuchsberger Christian, Facheris Maurizio F, Minelli Cosetta, Pattaro Cristian, Pramstaller Peter P, Hicks Andrew A

Abstract excerpt

BACKGROUND: Thyroid hormones have important roles in growth, development and control of metabolism, and their dysregulation can lead to disease. OBJECTIVES: To identify genes contributing to hyperthyrotropinaemia. DESIGN, SETTING, PARTICIPANTS: Linkage and association analyses using 1258 individuals from three Alpine villages. OUTCOME MEASURES: The study applied two different upper limits of the reference range...

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Identifiers

PMID: 21690246
DOI: 10.1136/jmg.2010.088583

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DACT2

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