Article
Partial evidence of an association between epidermal growth factor A61G polymorphism and age at onset in male schizophrenia.
Neuroscience research - 1 Dec 2006
Lee Kyu Young, Ahn Yong Min, Joo Eun-Jeong, Joo Yeon Ho, Chang Jae Seung, Yoo Han Young, Kim Yong Sik
Abstract excerpt
Epidermal growth factor (EGF) is a well-known neurotrophic factor regulating the development of various neuronal cells, including dopaminergic neurons, and dysfunction of EGF signals has been demonstrated as a risk factor for schizophrenia. Recently, several researchers have investigated associations including age at onset (AAO) with EGF A61G functional polymorphism, but the results of these studies have been...
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