Article
Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice.
Cell and tissue research - 1 Jul 2011
Ehninger Dan, Wang Li-Ping, Klempin Friederike, Römer Benedikt, Kettenmann Helmut, Kempermann Gerd
Abstract excerpt
Proliferative cells expressing proteoglycan neuron-glia 2 (NG2) are considered to represent parenchymal precursor cells in the adult brain and are thought to differentiate primarily into oligodendrocytes. We have studied cell genesis in the adult amygdala and found that, up to 1 year after the labeling of proliferating cells with bromodeoxyuridine, most proliferating NG2 cells remain NG2 cells, and only a few...
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