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Article

Seizures preferentially stimulate proliferation of radial glia-like astrocytes in the adult dentate gyrus: functional and immunocytochemical analysis.

The European journal of neuroscience - 1 Nov 2003

Hüttmann Kerstin, Sadgrove Matthew, Wallraff Anke, Hinterkeuser Stefan, Kirchhoff Frank, Steinhäuser Christian, Gray William P

Abstract excerpt

Kainate-induced seizures increase hippocampal neurogenesis. Glial fibrillary acidic protein-positive astrocytes with radial processes in the dentate gyrus share many of the characteristics of radial glia and appear to act as precursor cells for adult dentate neurogenesis. Using the chemoconvulsant kainate and transgenic mice with human glial-fibrillary acidic protein (hGFAP) promoter-controlled enhanced green...

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PMID: 14656326
DOI: 10.1111/j.1460-9568.2003.03002.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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