Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.

PloS one - 1 Jan 2011

Chen Changchun, Huang Bo, Anderson James T, Byström Anders S

Abstract excerpt

BACKGROUND: Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the maturation process, a subset of the nucleosides are modified. Modifications in the anticodon region often modulate the decoding ability of the tRNA. At position 34, the majority of yeast cytosolic tRNA species that have a uridine are modified to 5-carbamoylmethyluridine (ncm(5)U),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Esterification
Share to Mutation
Share to RNA, Transfer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to tRNA Methyltransferases

Share to Uridine

Source

Open in PubMed Open full text

Identifiers

PMID: 21687733
DOI: 10.1371/journal.pone.0020783
PMCID: PMC3110198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unexpected accumulation of ncm(5)U and ncm(5)S(2) (U) in a trm9 mutant suggests an additional step in the synthesis of mcm(5)U and mcm(5)S(2)U.PMID 21687733Read ↗

Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation.Semantic proximity Read ↗

Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast.Semantic proximity Read ↗

Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae.Semantic proximity Read ↗

Roles of Trm9- and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.Semantic proximity Read ↗

Methylated nucleosides in tRNA and tRNA methyltransferasesSemantic proximity Read ↗

Initiator tRNA lacking 1-methyladenosine is unexpectedly targeted by the rapid tRNA decay pathway in evolutionarily distant yeast speciesSemantic proximity Read ↗

A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast.Semantic proximity Read ↗

Novel methyltransferase for modified uridine residues at the wobble position of tRNA.Semantic proximity Read ↗

Identification of a motif in Trm732 required for 2’- <i>O</i> -methylation of the tRNA anticodon loop by Trm7Semantic proximity Read ↗

Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.Semantic proximity Read ↗

TRMT2B is responsible for both tRNA and rRNA m <sup>5</sup> U-methylation in human mitochondriaSemantic proximity Read ↗

Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.