Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Jun 1990

Yoshida H, Bogaki M, Nakamura M, Nakamura S

Abstract excerpt

Nucleotide sequence analysis of the gyrA genes of 10 spontaneous quinolone-resistant gyrA mutants of Escherichia coli KL16, including four mutants examined previously, disclosed that quinolone resistance was caused by a point mutation within the region between amino acids 67 and 106, especially in the vicinity of amino acid 83, of the GyrA protein.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 4-Quinolones
Share to Anti-Infective Agents
Share to DNA Topoisomerases, Type II

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Escherichia coli

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 2168148
DOI: 10.1128/AAC.34.6.1271
PMCID: PMC171799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.PMID 2168148Read ↗

Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli.Semantic proximity Read ↗

Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus.Semantic proximity Read ↗

Mutations in the gyrA and grlA genes of quinolone-resistant clinical isolates of methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

Analysis of the NH2-terminal 83rd amino acid of Escherichia coli GyrA in quinolone-resistance.Semantic proximity Read ↗

4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reactionSemantic proximity Read ↗

Mutation in the DNA gyrase A Gene of Escherichia coli that expands the quinolone resistance-determining region.Semantic proximity Read ↗

Mutation in the gyrA gene of quinolone-resistant clinical isolates of Acinetobacter baumannii.Semantic proximity Read ↗

Mechanism of quinolone resistance in Staphylococcus aureus.Semantic proximity Read ↗

Molecular cloning of the gyrA gene and characterization of its mutation in clinical isolates of quinolone-resistant Edwardsiella tarda.Semantic proximity Read ↗

Cloning and nucleotide sequence of the DNA gyrase (gyrA) gene from Mycoplasma hominis and characterization of quinolone-resistant mutants selected in vitro with trovafloxacin.Semantic proximity Read ↗

Interaction between DNA gyrase and quinolones: effects of alanine mutations at GyrA subunit residues Ser(83) and Asp(87).Semantic proximity Read ↗

DNA gyrase mutations in quinolone-resistant clinical isolates of Neisseria gonorrhoeae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.