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Article

Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Aug 1991

Yoshida H, Bogaki M, Nakamura M, Yamanaka L M, Nakamura S

Abstract excerpt

Thirteen spontaneous quinolone-resistant gyrB mutants of Escherichia coli KL16, including two that were examined previously, were divided into two types according to their quinolone resistance patterns. Type 1 mutants were resistant to all the quinolones tested, while type 2 mutants were resistant to acidic quinolones and were hypersusceptible to amphoteric quinolones. Nucleotide sequence analysis disclosed that...

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Identifiers

PMID: 1656869
DOI: 10.1128/AAC.35.8.1647
PMCID: PMC245234

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