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Article

Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies.

Cancer prevention research (Philadelphia, Pa.) - 1 Nov 2011

Lee Jung Eun, Baba Yoshifumi, Ng Kimmie, Giovannucci Edward, Fuchs Charles S, Ogino Shuji, Chan Andrew T

Abstract excerpt

Use of statins is hypothesized to reduce colorectal cancer risk but the evidence remains inconsistent. This may be partly explained by differential associations according to tumor location or molecular subtypes of colorectal cancer. We examined the association between statin use and colorectal cancer risk according to tumor location, KRAS mutation status, microsatellite instability (MSI) status, PTGS2 (COX-2)...

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Source

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Identifiers

PMID: 21680706
DOI: 10.1158/1940-6207.CAPR-11-0113
PMCID: PMC3192239

Genes

KRAS
PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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