Article
Association between molecular subtypes of colorectal cancer and patient survival.
Gastroenterology - 1 Jan 2015
Phipps Amanda I, Limburg Paul J, Baron John A, Burnett-Hartman Andrea N, Weisenberger Daniel J, Laird Peter W, Sinicrope Frank A, Rosty Christophe, Buchanan Daniel D, Potter John D, Newcomb Polly A
Abstract excerpt
BACKGROUND AND AIMS: Colorectal cancer (CRC) is a heterogeneous disease that can develop via several pathways. Different CRC subtypes, identified based on tumor markers, have been proposed to reflect these pathways. We evaluated the significance of these previously proposed classifications to sur...
Topics
- Adult
- Aged
- Biomarkers, Tumor
- Colorectal Neoplasms
- CpG Islands
- DNA Methylation
- DNA Mutational Analysis
- Disease-Free Survival
- Female
- Genetic Predisposition to Disease
- Humans
- Kaplan-Meier Estimate
- Male
- Microsatellite Instability