Article
Risk Factors and Incidence of Colorectal Cancer According to Major Molecular Subtypes.
JNCI cancer spectrum - 1 Feb 2021
Wang Liang, He Xiaosheng, Ugai Tomotaka, Haruki Koichiro, Lo Chun-Han, Hang Dong, Akimoto Naohiko, Fujiyoshi Kenji, Wang Molin, Fuchs Charles S, Meyerhardt Jeffrey A, Zhang Xuehong, Wu Kana, Chan Andrew T, Giovannucci Edward L, Ogino Shuji, Song Mingyang
Abstract excerpt
Background: Colorectal cancer (CRC) is a heterogeneous disease that can develop via 3 major pathways: conventional, serrated, and alternate. We aimed to examine whether the risk factor profiles differ according to pathway-related molecular subtypes. Methods: We examined the association of 24 risk...
Topics
- Adiposity
- Age Factors
- Body Mass Index
- Cohort Studies
- Colorectal Neoplasms
- CpG Islands
- DNA Methylation
- Diet
- Female
- Follow-Up Studies
- Genes, ras
- Humans
- Incidence
- Life Style