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Article

Premature aging and cancer in nucleotide excision repair-disorders.

DNA repair - 15 Jul 2011

Diderich K, Alanazi M, Hoeijmakers J H J

Abstract excerpt

During the past decades, the major impact of DNA damage on cancer as 'disease of the genes' has become abundantly apparent. In addition to cancer, recent years have also uncovered a very strong association of DNA damage with many features of (premature) aging. The notion that DNA repair systems protect not only against cancer but also equally against to fast aging has become evident from a systematic, integral...

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Identifiers

PMID: 21680258
DOI: 10.1016/j.dnarep.2011.04.025
PMCID: PMC4128095

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