Article
DNA repair pathways and hereditary cancer susceptibility syndromes.
Frontiers in bioscience : a journal and virtual library - 1 May 2007
Spry Malinda, Scott Tim, Pierce Heather, D'Orazio John A
Abstract excerpt
Every living organism is exposed to numerous genomic insults on a daily basis as a consequence of cellular metabolism and exposure to environmental agents capable of interacting with the genome (e.g. chemicals, toxins, pollutants, UV and ionizing radiation) (1). Maintenance of the integrity of the genome is paramount to the survival and propagation of a species and involves the continuous activity of a variety of...
Topics
- DNA Repair
- Genetic Predisposition to Disease
- Humans
- Neoplasms
