Article
Changes in DNA repair during aging.
Nucleic acids research - 1 Jan 2007
Gorbunova Vera, Seluanov Andrei, Mao Zhiyong, Hine Christpher
Abstract excerpt
DNA is a precious molecule. It encodes vital information about cellular content and function. There are only two copies of each chromosome in the cell, and once the sequence is lost no replacement is possible. The irreplaceable nature of the DNA sets it apart from other cellular molecules, and makes it a critical target for age-related deterioration. To prevent DNA damage cells have evolved elaborate DNA repair...
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