Article
Divide and conquer: nucleotide excision repair battles cancer and ageing.
Current opinion in cell biology - 1 Apr 2003
Mitchell James R, Hoeijmakers Jan H J, Niedernhofer Laura J
Abstract excerpt
Protection from cancer and ensured longevity are tightly linked in mammals. One of the fundamental mechanisms contributing to both is the cellular response to DNA damage. The appropriate response is an initial attempt at repair, but if the damage is too extensive or compromises DNA metabolism, a...
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