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Article

XIAP‐associated factor 1 (XAF1), a novel target of p53, enhances p53‐mediated apoptosis via post‐translational modification

15 Jun 2011

Abstract excerpt

The role of X chromosome-linked inhibitor of apoptosis protein (XIAP)-associated factor 1 (XAF1) in mediating apoptosis has been reported but the underlying mechanism remains unclear. The present study was designed to examine the putative interaction between XAF1 and p53 and the functional importance of this interaction in regulation of apoptosis in human gastric and colon cancer cells. We first identified XAF1...

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PMID: 21678496
DOI: 10.1002/mc.20807

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XIAP‐associated factor 1 (XAF1), a novel target of p53, enhances p53‐mediated apoptosis via post‐translational modificationPMID 21678496Read ↗

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