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Article

Identification of a functional p53 responsive element within the promoter of XAF1 gene in gastrointestinal cancer cells.

International journal of oncology - 1 Apr 2010

Zhang Wenjing, Guo Zheng, Jiang Bo, Niu Lingyun, Xia Guosheng, Wang Xinying, Cheng Tianming, Zhang Yusheng, Wang Jide

Abstract excerpt

It has been reported that XAF1 expression in gastric cancer is negatively correlated with p53. Our purpose was to clarify the regulatory mechanism of p53 on XAF1 expression. The effects of overexpressed wild-type and mutant p53 on XAF1 expression were evaluated. Binding capacity of core XAF1 prom...

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Source

Identifiers

PMID: 20198350
DOI: 10.3892/ijo_00000584

Genes

XAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20198350-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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