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Article

XIAP’s Profile in Human Cancer

29 Oct 2020

Abstract excerpt

XIAP, the X-linked inhibitor of apoptosis protein, regulates cell death signaling pathways through binding and inhibiting caspases. Mounting experimental research associated with XIAP has shown it to be a master regulator of cell death not only in apoptosis, but also in autophagy and necroptosis. As a vital decider on cell survival, XIAP is involved in the regulation of cancer initiation, promotion and...

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PMID: 33138314
DOI: 10.3390/biom10111493

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