Article
Lack of association of the genotype in the GNAS Fok I polymorphism and prostate cancer.
Urologia internationalis - 1 Jan 2011
Eisenhardt A, Scherag A, Jöckel K H, Reis H, Rübben H, Siffert W
Abstract excerpt
BACKGROUND: G proteins are ubiquitously expressed signal transduction proteins playing a key role in multiple signal transduction pathways. The Gαs subunit has been considered as an apoptosis factor. In this study the role of GNAS T393C genotypes of the GNAS gene encoding Gαs was analyzed for its influence on the development and progression of prostate cancer. METHODS: Genotyping of the GNAS T393C polymorphism in...
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