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Article

Lack of involvement of the GNAS1 T393C polymorphism in prostate cancer risk in a Japanese population.

Anticancer research - 1 Jan 2000

Watanabe Masatoshi, Hirokawa Yoshifumi, Tsuji Mayumi, Yanagawa Makoto, Murata Tetsuya, Suzuki Hiroyoshi, Ichikawa Tomohiko, Katoh Takahiko, Sugimura Yoshiki, Shiraishi Taizo

Abstract excerpt

BACKGROUND: GNAS1 encodes the a-subunit of the Gs protein (Gsa), which binds GTP and stimulates adenylyl cyclase. Activating mutations lead to somatotroph, thyroid, adrenal and gonadal adenomas or the McCune-Albright syndrome and recently the T399C polymorphism in GNAS1 has been reported to be associated with malignancies. The purpose of the present case-control study with 349 Japanese prostate cancer patients...

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PMID: 19189654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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