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Article

G Protein β3 subunit gene C825T polymorphism and its association with the presence and clinicopathological characteristics of prostate cancer.

The Journal of urology - 1 Jul 2012

Safarinejad Mohammad Reza, Safarinejad Shiva, Shafiei Nayyer, Safarinejad Saba

Abstract excerpt

PURPOSE: A C825T polymorphism in the GNB3 gene encodes the Gβ3 subunit of heterotrimeric G proteins. Due to increased G protein activation the GNB3 825T allele, a truncated form of the G3 protein, is associated with enhanced signal transduction capacity. This splice variant is associated with various malignant diseases. We investigated the possible association of GNB3 gene polymorphism with prostate cancer and...

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Source

Identifiers

PMID: 22608746
DOI: 10.1016/j.juro.2012.02.2557

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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G Protein β3 subunit gene C825T polymorphism and its association with the presence and clinicopathological characteristics of prostate cancer.PMID 22608746Read ↗

[Genotype of the GNB3 C825T polymorphism, A risk factor for the development and course of prostate cancer?].Semantic proximity Read ↗

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The G protein beta3 subunit 825T allele is a genetic marker for enhanced T cell response.Semantic proximity Read ↗

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