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Article

PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jun 2011

Bradshaw Nicholas J, Soares Dinesh C, Carlyle Becky C, Ogawa Fumiaki, Davidson-Smith Hazel, Christie Sheila, Mackie Shaun, Thomson Pippa A, Porteous David J, Millar J Kirsty

Abstract excerpt

Nuclear distribution factor E-homolog 1 (NDE1), Lissencephaly 1 (LIS1), and NDE-like 1 (NDEL1) together participate in essential neurodevelopmental processes, including neuronal precursor proliferation and differentiation, neuronal migration, and neurite outgrowth. NDE1/LIS1/NDEL1 interacts with Disrupted in Schizophrenia 1 (DISC1) and the cAMP-hydrolyzing enzyme phosphodiesterase 4 (PDE4). DISC1, PDE4, NDE1, and...

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Identifiers

PMID: 21677187
DOI: 10.1523/JNEUROSCI.5410-10.2011
PMCID: PMC3610090

Genes

NDE1
NDEL1
DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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