Article

The Role of Nde1 Phosphorylation in Interkinetic Nuclear Migration and Schizophrenia

2024-02-26

Abstract excerpt

Nde1 is a cytoplasmic dynein regulatory protein with important roles in vertebrate brain development. One noteworthy function is in the nuclear oscillatory behavior in neural progenitor cells, the control and mechanism of which remain poorly understood. Nde1 contains multiple phosphorylation sites for the cell cycle-dependent protein kinase CDK1, though the function of these sites is not well understood. To test t...

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Literature Corpus work: c4b858fe-8048-5e67-8c91-7d9db2306c59
DOI: 10.1101/2024.02.25.581986

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