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Article

Functional characteristics and research trends of PDE11A in human diseases (Review).

Molecular medicine reports - 1 Oct 2022

Kong Gyeyeong, Lee Hyunji, Vo Thuy-Trang T, Juang Uijin, Kwon So Hee, Park Jisoo, Park Jongsun, Kim Seon-Hwan

Abstract excerpt

cAMP and cGMP are important secondary messengers involved in cell regulation and metabolism driven by the G protein‑coupled receptor. cAMP is converted via adenylyl cyclase (AC) and activates protein kinase A to phosphorylate intracellular proteins that mediate specific responses. cAMP signaling serves a role at multiple steps in tumorigenesis. The level of cAMP is increased in association with cancer cell...

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Identifiers

PMID: 35929507
DOI: 10.3892/mmr.2022.12814
PMCID: PMC9434997

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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