Article
Transcription-replication collision increases recombination efficiency between plasmids.
Plasmid - 1 Nov 2013
Jialiang Li, Feng Chen, Zhen Xu, Jibing Chen, Xiang Lv, Lingling Zhang, Depei Liu
Abstract excerpt
It has been proposed that the stalling of the replication forks can induce homologous recombination in several organisms, and that arrested replication forks may offer nuclease targets, thereby providing a substrate for proteins involved in double-strand repair. In this article, we constructed a plasmid with the potential for transcription-replication collision (TRC), in which DNA replication and RNA...
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