Article
Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos.
Journal of virology - 1 Sept 1990
Flemington E, Speck S H
Abstract excerpt
The Epstein-Barr virus BZLF1 gene product ZEBRA is a DNA-binding protein that is partially homologous to c-Fos, binds specifically to AP-1 sites, and can induce the lytic cycle in latently infected B lymphocytes. Induction of the viral lytic cycle can also be achieved by treatment with the phorbo...
Topics
- Base Sequence
- Cell Line
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- HeLa Cells
- Herpesvirus 4, Human
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-fos
- Proto-Oncogenes
- Sequence Homology, Nucleic Acid
- Trans-Activators
- Viral Proteins