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Article

bZIP proteins of human gammaherpesviruses

16 Jul 2003

Abstract excerpt

The human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) both infect lymphoid and epithelial cells and both are implicated in the development of cancer. The two viruses establish latency in B-lymphoid cells that, once disrupted, leads to a burst of virus replication during the lytic cycle. A basic leucine zipper (bZIP) transcription factor encoded by EBV, Zta (also...

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PMID: 12867624
DOI: 10.1099/vir.0.19112-0

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