Identification of a negative cis element within the ZII domain of the Epstein-Barr virus lytic switch BZLF1 gene promoter.

doi:10.1128/JVI.72.10.8230-8239.1998

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Article

Identification of a negative cis element within the ZII domain of the Epstein-Barr virus lytic switch BZLF1 gene promoter.

Journal of virology - 1 Oct 1998

Liu P, Liu S, Speck S H

Abstract excerpt

The Epstein-Barr virus (EBV) lytic switch gene, BZLF1, is tightly regulated in latently infected B cells. The BZLF1 gene promoter (Zp) contains several cis elements that have been previously shown to respond to inducers of the viral lytic cycle. These include four copies of an element referred to...

Topics

Activating Transcription Factor 1
Activating Transcription Factor 2
Base Sequence
Cyclic AMP Response Element-Binding Protein
DNA, Viral
DNA-Binding Proteins
Herpesvirus 4, Human
Ionomycin
Mutation
Promoter Regions, Genetic
Protein Binding
Tetradecanoylphorbol Acetate
Trans-Activators
Transcription Factors
Tumor Cells, Cultured
Viral Proteins

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Identifiers

PMID: 9733866
DOI: 10.1128/JVI.72.10.8230-8239.1998
PMCID: PMC110177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9733866-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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