Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein Kinase C-Independent Activation of the Epstein-Barr Virus Lytic Cycle

1 Jun 2002

Abstract excerpt

The protein kinase C (PKC) pathway has been considered to be essential for activation of latent Epstein-Barr virus (EBV) into the lytic cycle. The phorbol ester tetradecanoyl phorbol acetate (TPA), a PKC agonist, is one of the best understood activators of EBV lytic replication. Zp, the promoter of the EBV immediate-early gene BZLF1, whose product, ZEBRA, drives the lytic cycle, contains several phorbol ester...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Disorders and Syndromes
Share to Lymphoma Diagnosis and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11991990
DOI: 10.1128/jvi.76.11.5612-5626.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein Kinase C-Independent Activation of the Epstein-Barr Virus Lytic CyclePMID 11991990Read ↗

ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus.Semantic proximity Read ↗

De Novo Protein Synthesis Is Required for Lytic Cycle Reactivation of Epstein-Barr Virus, but Not Kaposi's Sarcoma-Associated Herpesvirus, in Response to Histone Deacetylase Inhibitors and Protein Kinase C AgonistsSemantic proximity Read ↗

The Epstein-Barr virus ZEBRA protein activates transcription from the early lytic F promoter by binding to a promoter-proximal AP-1-like site.Semantic proximity Read ↗

Differences in the extent of activation of Epstein-Barr virus replicative gene expression among four nonproducer cell lines stably transformed by oriP/BZLF1 plasmids.Semantic proximity Read ↗

Mutant Cellular AP-1 Proteins Promote Expression of a Subset of Epstein-Barr Virus Late Genes in the Absence of Lytic Viral DNA Replication.Semantic proximity Read ↗

The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II MoleculesSemantic proximity Read ↗

Lytic cycle gene regulation of Epstein-Barr virus.Semantic proximity Read ↗

Essential Role of Rta in Lytic DNA Replication of Epstein-Barr VirusSemantic proximity Read ↗

Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cellsSemantic proximity Read ↗

Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic ReplicationSemantic proximity Read ↗

Qualitative analysis of the expression of Epstein--Barr virus lytic genes in nasopharyngeal carcinoma biopsiesSemantic proximity Read ↗

Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.