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Article

ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus.

PLoS pathogens - 1 Dec 2007

Yu Xianming, Wang Zhenxun, Mertz Janet E

Abstract excerpt

The immediate-early (IE) BZLF1 gene of Epstein-Barr virus (EBV) regulates the switch between latent and lytic infection by EBV. We previously showed that the cellular transcription factor ZEB1 binds to a sequence element, ZV, located at nt -17 to -12 relative to the transcription initiation site of the BZLF1 promoter, Zp, repressing transcription from Zp in a transient transfection assay. Here, we report the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Herpesvirus 4, Human

Share to Kruppel-Like Transcription Factors

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Source

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Identifiers

PMID: 18085824
DOI: 10.1371/journal.ppat.0030194
PMCID: PMC2134958

Genes

ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus.PMID 18085824Read ↗

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Identification of a negative cis element within the ZII domain of the Epstein-Barr virus lytic switch BZLF1 gene promoter.Semantic proximity Read ↗

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