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Article

PAPC and the Wnt5a/Ror2 pathway control the invagination of the otic placode in Xenopus.

BMC developmental biology - 10 Jun 2011

Jung Barbara, Köhler Almut, Schambony Alexandra, Wedlich Doris

Abstract excerpt

BACKGROUND: Paraxial protocadherin (PAPC) plays a crucial role in morphogenetic movements during gastrulation and somitogenesis in mouse, zebrafish and Xenopus. PAPC influences cell-cell adhesion mediated by C-Cadherin. A putative direct adhesion activity of PAPC is discussed. PAPC also promotes cell elongation, tissue separation and coordinates cell mass movements. In these processes the signaling function of...

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Identifiers

PMID: 21663658
DOI: 10.1186/1471-213X-11-36
PMCID: PMC3127988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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