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Article

PAPC couples the segmentation clock to somite morphogenesis by regulating N-cadherin-dependent adhesion.

Development (Cambridge, England) - 15 Feb 2017

Chal Jérome, Guillot Charlène, Pourquié Olivier

Abstract excerpt

Vertebrate segmentation is characterized by the periodic formation of epithelial somites from the mesenchymal presomitic mesoderm (PSM). How the rhythmic signaling pulse delivered by the segmentation clock is translated into the periodic morphogenesis of somites remains poorly understood. Here, we focused on the role of paraxial protocadherin (PAPC/Pcdh8) in this process. We showed that in chicken and mouse...

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Source

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Identifiers

PMID: 28087631
DOI: 10.1242/dev.143974
PMCID: PMC5312037

Genes

CDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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