Article
Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin.
Developmental biology - 1 Oct 1995
Lee C H, Gumbiner B M
Abstract excerpt
Gastrulation in Xenopus laevis transforms a ball of undifferentiated cells into a well-organized elongated embryo with a distinct body axis, as a result of extensive cell rearrangements and movements. Since cell adhesion is thought to play an important role during tissue morphogenesis, we investigated the potential role for C-cadherin, a primary cell-cell adhesion molecule in Xenopus, in gastrulation movements. A...
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