Article
Epigenomic reprogramming of the developing reproductive tract and disease susceptibility in adulthood
7 Jun 2011
Abstract excerpt
During development, epigenetic programs are "installed" on the genome that direct differentiation and normal tissue and organ function in adulthood. Consequently, development is also a period of susceptibility to reprogramming of the epigenome. Developmental reprogramming occurs when an adverse stimulus or insult interrupts the proper "install" of epigenetic programs during development, reprogramming normal...
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