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Minireview: Epigenomic Plasticity and Vulnerability to EDC Exposures

29 Jun 2016

Abstract excerpt

The epigenome undergoes significant remodeling during tissue and organ development, which coincides with a period of exquisite sensitivity to environmental exposures. In the case of endocrine-disrupting compounds (EDCs), exposures can reprogram the epigenome of developing tissues to increase susceptibility to diseases later in life, a process termed "developmental reprogramming." Both DNA methylation and histone...

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PMID: 27355193
DOI: 10.1210/me.2016-1086

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