Article

Neonatal diethylstilbestrol exposure disrupts uterine epithelial apical-basal polarity and partial EMT state

2026-02-02

Abstract excerpt

The developing female reproductive tract is highly sensitive to external hormonal stimulation, which can result in infertility and gynecologic diseases. To determine the underlying mechanisms, we used a mouse model to test the immediate, cell type-specific effects of neonatal exposure to the estrogenic chemical, diethylstilbestrol (DES), on the developing uterus. We found that control uterine epithelium is in a pa...

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Literature Corpus work: 8515ddf7-a3ac-5513-84a1-7ab7d969bd75
DOI: 10.64898/2026.01.29.702663

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