Article
Mutations of mitochondrial DNA and human death.
Die Naturwissenschaften - 1 May 1990
Kadenbach B, Müller-Höcker J
Abstract excerpt
In the skeletal muscle of patients with mitochondrial myopathies (Kearns-Sayre syndrome and chronic progressive external ophthalmoplegia) and in the heart and skeletal muscle of healthy persons cells lacking cytochrome c oxidase are found. The respiratory-defective cells have the following featur...
Topics
- Animals
- Cytochrome-c Oxidase Deficiency
- DNA, Mitochondrial
- Death
- Electron Transport Complex IV
- Humans
- Mammals
- Mitochondria, Heart
- Mitochondria, Muscle
- Muscular Diseases
- Mutation
- Reference Values