Article
Mitochondrial DNA mutations and age.
Annals of the New York Academy of Sciences - 20 Nov 1998
Ozawa T
Abstract excerpt
Apopotic cell death is reported to be prominent in the stable tissues of the failing heart, in cardiomyopathies (CM), in the sinus node of complete heart block, in B cells of diabetes mellitus, and in neurodegenerative diseases. Recently, mitochondrial (mt) control of nuclear apoptosis was demons...
Topics
- Aging
- Animals
- Apoptosis
- DNA Fragmentation
- DNA, Mitochondrial
- Heart Diseases
- Humans
- Mutation
- Neurodegenerative Diseases
- Oxidative Stress
- Point Mutation
- Sequence Deletion
