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Article

Mitochondrial DNA mutations and age.

Annals of the New York Academy of Sciences - 20 Nov 1998

Ozawa T

Abstract excerpt

Apopotic cell death is reported to be prominent in the stable tissues of the failing heart, in cardiomyopathies (CM), in the sinus node of complete heart block, in B cells of diabetes mellitus, and in neurodegenerative diseases. Recently, mitochondrial (mt) control of nuclear apoptosis was demonstrated in the cell-free system. The mt bioenergetic crisis induced by exogenously added factors such as respiratory...

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Identifiers

PMID: 9928426
DOI: 10.1111/j.1749-6632.1998.tb09898.x

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