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Article

Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle.

Free radical biology & medicine - 1 Jun 2001

Pesce V, Cormio A, Fracasso F, Vecchiet J, Felzani G, Lezza A M, Cantatore P, Gadaleta M N

Abstract excerpt

To have a clearer picture of how mitochondrial damages are associated to aging, a comprehensive study of phenotypic and genotypic alterations was carried out, analyzing with histochemical and molecular biology techniques the same skeletal muscle specimens of a large number of healthy subjects from 13 to 92 years old. Histochemical data showed that ragged red fibers (RRF) appear at about 40 years of age and are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11368920
DOI: 10.1016/s0891-5849(01)00517-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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