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Article

Association of the interleukin-22 genetic polymorphisms with ulcerative colitis.

Diagnostic pathology - 9 Oct 2014

Chi Hong Gang, Zheng Xue Bao, Wu Zhu Guo, Dai Shi Xue, Wan Zheng, Zou Ying

Abstract excerpt

BACKGROUND: Interleukin-22 (IL-22) is a member of the IL-10 family of anti-inflammatory cytokines that mediates epithelial immunity. IL-22 expression was found to be increased in patients with ulcerative colitis (UC). Whether genetic polymorphisms of IL-22 also influence UC risk is still unknown. The purpose of this study was to investigate the association between the IL-22 gene polymorphisms (-429 C/T, +1046 T/A...

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Identifiers

PMID: 25297677
DOI: 10.1186/s13000-014-0183-y
PMCID: PMC4198677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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