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Article

Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.

Digestion - 1 Jan 2011

Stallhofer Johannes, Denk Gerald Ulrich, Glas Jürgen, Laubender Rüdiger Paul, Göke Burkhard, Rust Christian, Brand Stephan, Pusl Thomas

Abstract excerpt

BACKGROUND/AIMS: The chromosome 4q27 region harboring IL2 and IL21 is an established risk locus for ulcerative colitis (UC) and various other autoimmune diseases. Considering the strong coincidence of primary sclerosing cholangitis (PSC) with UC and the increased frequency of other autoimmune disorders in patients with primary biliary cirrhosis (PBC), we investigated whether genetic variation in the IL2/IL21...

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PMID: 21304239
DOI: 10.1159/000321619

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Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.PMID 21304239Read ↗

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