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Article

The RuvABC resolvasome.

European journal of biochemistry - 1 Nov 2002

Dickman Mark J, Ingleston Stuart M, Sedelnikova Svetlana E, Rafferty John B, Lloyd Robert G, Grasby Jane A, Hornby David P

Abstract excerpt

The RuvABC resolvasome of Escherichia coli catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair. This process involves two key steps: branch migration, catalysed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein, and resolution, which is catalysed by the RuvC endonuclease. We have quantified the interaction of the...

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PMID: 12423347
DOI: 10.1046/j.1432-1033.2002.03250.x

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Research trail→

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The RuvABC resolvasome.PMID 12423347Read ↗

Genetic recombination in E. coli: RuvC protein cleaves Holliday junctions at resolution hotspots in vitro.Semantic proximity Read ↗

Analysis of conserved basic residues associated with DNA binding (Arg69) and catalysis (Lys76) by the RusA holliday junction resolvase.Semantic proximity Read ↗

Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure.Semantic proximity Read ↗

Mycobacterium tuberculosis RuvA induces two distinct types of structural distortions between the homologous and heterologous Holliday junctions.Semantic proximity Read ↗

Genetic analysis of an archaeal Holliday junction resolvase in Escherichia coli.Semantic proximity Read ↗

Molecular mechanisms of Holliday junction processing in Escherichia coli.Semantic proximity Read ↗

Two basic residues, Lys-107 and Lys-118, of RuvC resolvase are involved in critical contacts with the Holliday junction for its resolution.Semantic proximity Read ↗

Escherichia coli RuvBL268S: a mutant RuvB protein that exhibits wild-type activities in vitro but confers a UV-sensitive ruv phenotype in vivo.Semantic proximity Read ↗

The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis.Semantic proximity Read ↗

The structure of Escherichia coli RusA endonuclease reveals a new Holliday junction DNA binding fold.Semantic proximity Read ↗

The RuvABC resolvase is indispensable for recombinational repair in sbcB15 mutants of Escherichia coli.Semantic proximity Read ↗

Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA.Semantic proximity Read ↗

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