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Article

Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes.

Molecular cancer therapeutics - 1 Aug 2004

Maglione Jeannie E, McGoldrick Erik T, Young Lawrence J T, Namba Ruria, Gregg Jeffrey P, Liu Lin, Moghanaki Drew, Ellies Lesley G, Borowsky Alexander D, Cardiff Robert D, MacLeod Carol L

Abstract excerpt

The development of models to investigate the pathobiology of premalignant breast lesions is a critical prerequisite for development of breast cancer prevention and early intervention strategies. Using tissue transplantation techniques, we modified the widely used polyomavirus middle T (PyV-mT) transgenic mouse model of breast cancer to study the premalignant stages of tumorigenesis. Premalignant atypical lesions...

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PMID: 15299077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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