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Article

Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation.

Psychiatric genetics - 1 Dec 2011

Hill Matthew James, Kenny Elaine, Roche Siobhan, Morris Derek W, Corvin Aiden, Hawi Ziarih, Gill Michael, Anney Richard J L

Abstract excerpt

OBJECTIVE: To identify cis-acting regulatory variants influencing the expression of the schizophrenia susceptibility gene chitinase 3-like 1 gene (CHI3L1) in human lymphoblasts and post-mortem brain tissue. METHODS: To investigate the role of cis-acting regulatory variants in controlling gene expression of CHI3L1 we quantified relative allelic abundance in individuals heterozygous for the transcribed polymorphism...

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PMID: 21642896
DOI: 10.1097/YPG.0b013e328348045b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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