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Article

Failure to confirm genetic association of the CHI3L1 gene with schizophrenia in Japanese and Chinese populations.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2009

Yamada Kazuo, Hattori Eiji, Iwayama Yoshimi, Toyota Tomoko, Ohnishi Tetsuo, Iwata Yasuhide, Tsuchiya Kenji J, Sugihara Genichi, Kikuchi Mitsuru, Okazaki Yuji, Yoshikawa Takeo

Abstract excerpt

Recently, three common polymorphisms in the promoter region of the Chitinase 3-Like 1 (CHI3L1) gene, rs6691378, rs10399805 and rs4950928, have been identified as schizophrenia predisposing single nucleotide polymorphisms (SNPs) in the Han Chinese population. The at-risk haplotype comprising these SNPs was also related to decreased expression of CHI3L1 in peripheral blood cells. In contrast, two independent...

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PMID: 18767121
DOI: 10.1002/ajmg.b.30847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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