Article
Survey of the effect of genetic variations on gene expression in human prefrontal cortex and its application to genetics of psychiatric disorders.
Neuroscience research - 1 Jun 2011
Iwamoto Kazuya, Ueda Junko, Bundo Miki, Kojima Toshio, Kato Tadafumi
Abstract excerpt
Identifying the genetic basis of gene expression variation in the human brain is important for understanding brain physiology and pathophysiology. We investigated the genetic basis of gene expression variation in human prefrontal cortex using single nucleotide polymorphisms (SNPs) and taking into consideration brain sample pH. From approximately 12,000 brain-expressed transcripts, we identified 187 cis-regulated...
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